Inflammatory Bowel Diseases

Inflammatory bowel disease (IBD) represents an association of intestinal disorders that engender prolonged inflammation of the digestive tract. These are of two types: Ulcerative colitis and Crohn's disease. Ulcerative colitis causes long-lasting inflammation and sores (ulcers) in the innermost lining of  large intestine (colon) and rectum.

Crohn's disease is characterized by inflammation of the lining of digestive tract, which often spreads deep into affected tissues. Both ulcerative colitis and Crohn's disease usually involve severe diarrhea, abdominal pain, fatigue and weight loss.

 

·         Future IBD therapies

·         Understanding the use of IL12/IL23 targeted Biologics

·         The treatment of moderate to severe IBD with anti-TNF Biologics and Immunomodulators

·         Optimizing adhesion molecule-based therapies

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